Neuroprotection of NAD+ and NBP against ischemia/reperfusion brain injury is associated with restoration of sirtuin-regulated metabolic homeostasis

• Main Authors: Xin-Xin Wang (Author), Guang-Hui Mao (Author), Qi-Qi Li (Author), Jie Tang (Author), Hua Zhang (Author), Kang-Lin Wang (Author), Lei Wang (Author), Hong Ni (Author), Rui Sheng (Author), Zheng-Hong Qin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Ischemic stroke seriously threatens human health because of high rates of morbidity, mortality and disability. This study compared the effects of nicotinamide adenine dinucleotide (NAD+) and butylphthalide (NBP) on in vitro and in vivo ischemic stroke models.Methods: Transient middle cer...