Neuroprotection of NAD+ and NBP against ischemia/reperfusion brain injury is associated with restoration of sirtuin-regulated metabolic homeostasis

• Principais autores: Xin-Xin Wang (Autor), Guang-Hui Mao (Autor), Qi-Qi Li (Autor), Jie Tang (Autor), Hua Zhang (Autor), Kang-Lin Wang (Autor), Lei Wang (Autor), Hong Ni (Autor), Rui Sheng (Autor), Zheng-Hong Qin (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Ischemic stroke seriously threatens human health because of high rates of morbidity, mortality and disability. This study compared the effects of nicotinamide adenine dinucleotide (NAD+) and butylphthalide (NBP) on in vitro and in vivo ischemic stroke models.Methods: Transient middle cer...