Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia

• Главные авторы: Iki Sonn (Автор), Fumiko Honda-Ozaki (Автор), Sho Yoshimatsu (Автор), Satoru Morimoto (Автор), Hirotaka Watanabe (Автор), Hideyuki Okano (Автор)
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• Опубликовано: BMC, 2022-07-01T00:00:00Z.
• Предметы: article
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Abstract Background Microglia are innate immune cells that are the only residential macrophages in the central nervous system. They play vital physiological roles in the adult brain and during development. Microglia are particularly in the spotlight because many genetic risk factors recently identif...