Advancing humanized monoclonal antibody for counteracting fentanyl toxicity towards clinical development

• Main Authors: Dustin Hicks (Author), Carly Baehr (Author), Pedro Silva-Ortiz (Author), Aaron Khaimraj (Author), Diego Luengas (Author), Fatima A. Hamid (Author), Marco Pravetoni (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Innovative therapies to complement current treatments are needed to curb the growing incidence of fatal overdoses related to synthetic opioids. Murine and chimeric monoclonal antibodies (mAb) specific for fentanyl and its analogs have demonstrated pre-clinical efficacy in preventing and reversing dr...