In-vitro activity of avermectins against Mycobacterium ulcerans.

• Main Authors: Till F Omansen (Author), Jessica L Porter (Author), Paul D R Johnson (Author), Tjip S van der Werf (Author), Ymkje Stienstra (Author), Timothy P Stinear (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium ulcerans causes Buruli ulcer (BU), a debilitating infection of subcutaneous tissue. There is a WHO-recommended antibiotic treatment requiring an 8-week course of streptomycin and rifampicin. This regime has revolutionized the treatment of BU but there are problems that include reliance...