Single cell RNA sequencing reveals human tooth type identity and guides in vitro hiPSC derived odontoblast differentiation (iOB)

• Главные авторы: Sesha Hanson-Drury (Автор), Anjali P. Patni (Автор), Deborah L. Lee (Автор), Ammar Alghadeer (Автор), Yan Ting Zhao (Автор), Devon Duron Ehnes (Автор), Vivian N. Vo (Автор), Sydney Y. Kim (Автор), Druthi Jithendra (Автор), Ashish Phal (Автор), Natasha I. Edman (Автор), Thomas Schlichthaerle (Автор), David Baker (Автор), Jessica E. Young (Автор), Julie Mathieu (Автор), Hannele Ruohola-Baker (Автор)
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• Опубликовано: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Предметы: article
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Over 90% of the U.S. adult population suffers from tooth structure loss due to caries. Most of the mineralized tooth structure is composed of dentin, a material produced and mineralized by ectomesenchyme derived cells known as odontoblasts. Clinicians, scientists, and the general public share the de...