Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy

• Main Authors: Yancheng Tang (Author), Liming Wang (Author), Tao Yi (Author), Jun Xu (Author), Jigang Wang (Author), Jiang-Jiang Qin (Author), Qilei Chen (Author), Ka-Man Yip (Author), Yihang Pan (Author), Peng Hong (Author), Yingying Lu (Author), Han-Ming Shen (Author), Hu-Biao Chen (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondria as a signaling platform play crucial roles in deciding cell fate. Many classic anticancer agents are known to trigger cell death through induction of mitochondrial damage. Mitophagy, one selective autophagy, is the key mitochondrial quality control that effectively removes damaged mitoc...