Harnessing the Dual Antimicrobial Mechanism of Action with Fe(8-Hydroxyquinoline)₃ to Develop a Topical Ointment for Mupirocin-Resistant MRSA Infections

• Main Authors: Nalin Abeydeera (Author), Bogdan M. Benin (Author), Khalil Mudarmah (Author), Bishnu D. Pant (Author), Guanyu Chen (Author), Woo Shik Shin (Author), Min-Ho Kim (Author), Songping D. Huang (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

8-Hydroxyquinoline (8-hq) exhibits potent antimicrobial activity against <i>Staphylococcus aureus</i> (SA) bacteria with MIC = 16.0-32.0 µM owing to its ability to chelate metal ions such as Mn²⁺, Zn^2+, and Cu²⁺ to disr...