Pharmacokinetic Interaction of Paeoniflorin and Sinomenine: Pharmacokinetic Parameters and Tissue Distribution Characteristics in Rats and Protein Binding Ability In Vitro

• Main Authors: Zhong Qiu Liu (Author), Zhi Hong Jiang (Author), Kelvin Chan (Author), Hua Zhou (Author), Yuen Fan Wong (Author), Zhao Xiang Bian (Author), Hong Xi Xu (Author), Liang Liu (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The root of Paeonia lactiflora and the stem of Sinomenium acutum are two herbs widely used in Chinese herbal medicine for the treatment of inflammatory and arthritic diseases. Studies on the interaction of the active constituents of these herbs, i.e., paeoniflorin and sinomenine, in pharmacokinetic...