Preparation of hydroxy genkwanin nanosuspensions and their enhanced antitumor efficacy against breast cancer

• Main Authors: Hui Ao (Author), Yijing Li (Author), Haowen Li (Author), Yian Wang (Author), Meihua Han (Author), Yifei Guo (Author), Rongxing Shi (Author), Feng Yue (Author), Xiangtao Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hydroxy genkwanin (HGK), a flavonoid compound from natural resources, showed good inhibition against the growth of breast tumor cells. However, the poor solubility restricted the further study and the in vivo drug delivery of HGK. We prepared HGK nanosuspensions by antisolvent precipitation method a...