On placental and lactational transfer of IgG‐based therapeutic proteins - Current understanding and knowledge gaps from a clinical pharmacology perspective

• Main Authors: Daphne Guinn (Author), Katherine Kratz (Author), Kristie Baisden (Author), Sarah Ridge (Author), Sonaly McClymont (Author), Elimika Pfuma Fletcher (Author), Tamara Johnson (Author), Yow‐Ming Wang (Author)
• Format: Book
• Published: Wiley, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Maternal medication use may expose the developing fetus through placental transfer or the infant through lactational transfer. Because pregnant and lactating individuals have been historically excluded from early drug development trials, there is often limited to no human data available to...