Personalised, Rational, Efficacy-Driven Cancer Drug Dosing via an Artificial Intelligence SystEm (PRECISE): A Protocol for the PRECISE CURATE.AI Pilot Clinical Trial

• Main Authors: Benjamin Kye Jyn Tan (Author), Chong Boon Teo (Author), Xavier Tadeo (Author), Siyu Peng (Author), Hazel Pei Lin Soh (Author), Sherry De Xuan Du (Author), Vilianty Wen Ya Luo (Author), Aishwarya Bandla (Author), Raghav Sundar (Author), Dean Ho (Author), Theodore Wonpeum Kee (Author), Agata Blasiak (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Oncologists have traditionally administered the maximum tolerated doses of drugs in chemotherapy. However, these toxicity-guided doses may lead to suboptimal efficacy. CURATE.AI is an indication-agnostic, mechanism-independent and efficacy-driven personalised dosing platform that may o...