The Conventional Antihistamine Drug Cyproheptadine Lacks QT-interval-Prolonging Action in Halothane-Anesthetized Guinea Pigs: Comparison With Hydroxyzine

• Asıl Yazarlar: Kazuko Kobayashi (Yazar), Naoki Omuro (Yazar), Akira Takahara (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2014-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract.: Antihistamines are known to belong to the chemical class that may induce long QT syndrome. Among them, cyproheptadine has been shown to exert multifaceted actions on the ventricular repolarization phase; namely, shortening of the action potential duration at supratherapeutic concentration...