Mechanism of Multi-Organ Injury in Experimental COVID-19 and Its Inhibition by a Small Molecule Peptide

• Main Authors: Michael J. Paidas (Author), Natarajan Sampath (Author), Emma A. Schindler (Author), Daniela S. Cosio (Author), Chima Obianuju Ndubizu (Author), Nagarajarao Shamaladevi (Author), Jaclyn Kwal (Author), Suset Rodriguez (Author), Anis Ahmad (Author), Norma Sue Kenyon (Author), Arumugam R. Jayakumar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe disease from SARS-CoV-2 infection often progresses to multi-organ failure and results in an increased mortality rate amongst these patients. However, underlying mechanisms of SARS- CoV-2-induced multi-organ failure and subsequent death are still largely unknown. Cytokine storm, increased leve...