BMP4 Cooperates with Retinoic Acid to Induce the Expression of Differentiation Markers in Cultured Mouse Spermatogonia

• Egile Nagusiak: Yongguang Yang (Egilea), Yanmin Feng (Egilea), Xue Feng (Egilea), Shangying Liao (Egilea), Xiuxia Wang (Egilea), Haiyun Gan (Egilea), Lixian Wang (Egilea), Xiwen Lin (Egilea), Chunsheng Han (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2016-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Spermatogenesis is sustained by the proliferation and differentiation of spermatogonial stem cells (SSCs). However, the molecules controlling these processes remain largely unknown. Here, we developed a simplified high concentration serum-containing system for the culture of mouse SSCs. Analysis of...