BMP4 Cooperates with Retinoic Acid to Induce the Expression of Differentiation Markers in Cultured Mouse Spermatogonia

• Main Authors: Yongguang Yang (Author), Yanmin Feng (Author), Xue Feng (Author), Shangying Liao (Author), Xiuxia Wang (Author), Haiyun Gan (Author), Lixian Wang (Author), Xiwen Lin (Author), Chunsheng Han (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Spermatogenesis is sustained by the proliferation and differentiation of spermatogonial stem cells (SSCs). However, the molecules controlling these processes remain largely unknown. Here, we developed a simplified high concentration serum-containing system for the culture of mouse SSCs. Analysis of...