SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni.

• Main Authors: Jan Dvorák (Author), Susan T Mashiyama (Author), Mohammed Sajid (Author), Simon Braschi (Author), Melaine Delcroix (Author), Eric L Schneider (Author), Wilson H McKerrow (Author), Mahmoud Bahgat (Author), Elizabeth Hansell (Author), Patricia C Babbitt (Author), Charles S Craik (Author), James H McKerrow (Author), Conor R Caffrey (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Blood flukes of the genus Schistosoma are platyhelminth parasites that infect 200 million people worldwide. Digestion of nutrients from the host bloodstream is essential for parasite development and reproduction. A network of proteolytic enzymes (proteases) facilitates hydrolysis of host hemoglobin...