Neuropathogenesis of Japanese encephalitis in a primate model.

• Main Authors: Khin Saw Aye Myint (Author), Anja Kipar (Author), Richard G Jarman (Author), Robert V Gibbons (Author), Guey Chuen Perng (Author), Brian Flanagan (Author), Duangrat Mongkolsirichaikul (Author), Yvonne Van Gessel (Author), Tom Solomon (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Japanese encephalitis (JE) is a major cause of mortality and morbidity for which there is no treatment. In addition to direct viral cytopathology, the inflammatory response is postulated to contribute to the pathogenesis. Our goal was to determine the contribution of bystander effects and inflammato...