A pH/ROS dual-responsive system for effective chemoimmunotherapy against melanoma via remodeling tumor immune microenvironment

• Egile Nagusiak: Leilei Wang (Egilea), Shanshan He (Egilea), Rong Liu (Egilea), Yuan Xue (Egilea), Yuan Quan (Egilea), Rongying Shi (Egilea), Xueying Yang (Egilea), Qing Lin (Egilea), Xun Sun (Egilea), Zhirong Zhang (Egilea), Ling Zhang (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2024-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Chemotherapeutics can induce immunogenic cell death (ICD) in tumor cells, offering new possibilities for cancer therapy. However, the efficiency of the immune response generated is insufficient due to the inhibitory nature of the tumor microenvironment (TME). Here, we developed a pH/reactive oxygen...