Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells

Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells

Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout evolution and present in all studied organisms. In mammals, it shows a high co-localization with mitochondria, and it has been demonstrated to be involved in the homeostasis of key processes within the organel...

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Main Authors: Vedangi Hambardikar (Author), Mariona Guitart-Mampel (Author), Ernest R. Scoma (Author), Pedro Urquiza (Author), Gowda G. A. Nagana (Author), Daniel Raftery (Author), John A. Collins (Author), Maria E. Solesio (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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