Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells

• Asıl Yazarlar: Vedangi Hambardikar (Yazar), Mariona Guitart-Mampel (Yazar), Ernest R. Scoma (Yazar), Pedro Urquiza (Yazar), Gowda G. A. Nagana (Yazar), Daniel Raftery (Yazar), John A. Collins (Yazar), Maria E. Solesio (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout evolution and present in all studied organisms. In mammals, it shows a high co-localization with mitochondria, and it has been demonstrated to be involved in the homeostasis of key processes within the organel...