A Controlled Release Codelivery System of MSCs Encapsulated in Dextran/Gelatin Hydrogel with TGF-β3-Loaded Nanoparticles for Nucleus Pulposus Regeneration

• Main Authors: Yibo Gan (Author), Sukai Li (Author), Pei Li (Author), Yuan Xu (Author), Liyuan Wang (Author), Chen Zhao (Author), Bin Ouyang (Author), Bing Tu (Author), Chengmin Zhang (Author), Lei Luo (Author), Xiangdong Luo (Author), Xiumei Mo (Author), Qiang Zhou (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem cell- (MSC-) based therapy is regarded as a potential tissue engineering strategy to achieve nucleus pulposus (NP) regeneration for the treatment of intervertebral disc degeneration (IDD). However, it is still a challenge to induce MSC differentiation in NP-like cells when MSCs are...