Could Increased Expression of Hsp27, an "Anti-Inflammatory" Chaperone, Contribute to the Monocyte-Derived Dendritic Cell Bias towards Tolerance Induction in Breast Cancer Patients?

• Main Authors: Ana Paula Silva de Azevedo-Santos (Author), Mirtes Castelo Branco Rocha (Author), Sulayne Janayna Araujo Guimarães (Author), André Alvares Marques Vale (Author), Fabio Martins Laginha (Author), Flavia Raquel F. Nascimento (Author), Maria Aparecida Nagai (Author), Patrícia C. Bergami-Santos (Author), José Alexandre Marzagão Barbuto (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dendritic cells (DCs) are the most efficient antigen-presenting cells and link the innate immune sensing of the environment to the initiation of adaptive immune responses, which may be directed to either acceptance or elimination of the recognized antigen. In cancer patients, though DCs would be exp...