PHARMACOKINETIC-PHARMACODYNAMIC CORRELATION FOR MEROPENEM APPLIED TO A BURN CHILD USING A BIOANALYTICAL LIQUID CROMATOGRAPHIC METHOD

PHARMACOKINETIC-PHARMACODYNAMIC CORRELATION FOR MEROPENEM APPLIED TO A BURN CHILD USING A BIOANALYTICAL LIQUID CROMATOGRAPHIC METHOD

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Bioanalytical method for LC meropenem quantification in plasma was described. Good absolute recovery (higher than 90%), adequate linearity (0.2-50.0 μg/mL, r2=0.999), high sensitivity (LOQ: 0.2 μg/mL; LOD: 0.1μg/mL) and acceptable stability were shown. Interday/intraday precisions were 2.3%/2.0% and...

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Main Authors: Silvia R. C. J. Santos (Author), Cristina Sanches-Giraud (Author), Flávio F. de Souza (Author), David Gómez (Author), Edvaldo Campos (Author), Rodrigo Azevedo (Author), Marcus Ferreira (Author), Jorge Nascimento (Author)
Format: Book
Published: Formifarma, LDA., 2011-12-01T00:00:00Z.
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3rd Floor Main Library

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