Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum

• Main Authors: Lily E. Kisia (Author), Prakasha Kempaiah (Author), Samuel B. Anyona (Author), Elly O. Munde (Author), Angela O. Achieng (Author), John M. Ong'echa (Author), Christophe G. Lambert (Author), Kiprotich Chelimo (Author), Collins Ouma (Author), Douglas J. Perkins (Author), Evans Raballah (Author)
• Format: Book
• Published: BMC, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Severe malarial anemia (SMA) is a leading cause of malaria-related morbidity and mortality in children. The genetic factors that influence development of SMA and inefficient erythropoiesis, a central pathogenic feature of SMA, are only partially understood. Methods We performed a...