Glycnsisitin A: A promising bicyclic peptide against heart failure that facilitates TFRC-mediated uptake of iron in cardiomyocytes

• Main Authors: Jichao Zhou (Author), Yuanyuan Liu (Author), Xiaoli Wei (Author), Meng Yuan (Author), Xu Zhang (Author), Lingfeng Qin (Author), Bing Cui (Author), Pingping Li (Author), Jing Zhang (Author), Ziming Feng (Author), Jianshuang Jiang (Author), Xiang Yuan (Author), Ruibing Xu (Author), Zhimeng Zhang (Author), Peicheng Zhang (Author), Xiaowei Zhang (Author), Yanan Yang (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zhigancao decoction is a traditional prescription for treating irregular pulse and palpitations in China. As the monarch drug of Zhigancao decoction, the bioactive molecules of licorice against heart diseases remain elusive. We established the HRESIMS-guided method leading to the isolation of three...