Investigation of the effect of solubility increase at the main absorption site on bioavailability of BCS class II drug (risperidone) using liquisolid technique

• Auteur principal: Ahmed Khames (Auteur)
• Format: Livre
• Publié: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

BCS class II drugs usually suffer inadequate bioavailability as dissolution step is the absorption rate limiting step. In this work, the effect of solubility increase at the main absorption site for these drugs was investigated using risperidone as a drug model. Liquisolid technique was applied to p...