Protocatechuic aldehyde acts synergistically with dacarbazine to augment DNA double-strand breaks and promote apoptosis in cutaneous melanoma cells

• Main Authors: Junxia Pei (Author), Zhou Su (Author), Xin Zeng (Author), Ya Zhong (Author), Yamei Zhang (Author), Yixi Yang (Author), Qiuxia Lu (Author), Jian Li (Author), Yu Deng (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Despite rapid developments in immunotherapy and targeted therapy, dacarbazine (DTIC)-based chemotherapy still has been placed at the first-line for advanced melanoma patients who are after failure of immunotherapy or targeted therapy. However, the limited response rate and surviv...