Evolution of HLA-B Pharmacogenomics and the Importance of PGx Data Integration in Health Care System: A 10 Years Retrospective Study in Thailand

• Main Authors: Napatrupron Koomdee (Author), Chiraphat Kloypan (Author), Pimonpan Jinda (Author), Jiratha Rachanakul (Author), Thawinee Jantararoungtong (Author), Rattanaporn Sukprasong (Author), Santirhat Prommas (Author), Nutthan Nuntharadthanaphong (Author), Apichaya Puangpetch (Author), Maliheh Ershadian (Author), Shobana John (Author), Mohitosh Biswas (Author), Chonlaphat Sukasem (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The HLA-B is the most polymorphic gene, play a crucial role in drug-induced hypersensitivity reactions. There is a lot of evidence associating several risk alleles to life-threatening adverse drug reactions, and a few of them have been approved as valid biomarkers for predicting life-thr...