Pharmacokinetics of dipeptide anxiolytic GB-115 after oral administration in different animals species and humans

• Main Authors: S. Yu. Raskin (Author), G. B. Kolyvanov (Author), A. A. Litvin (Author), P. O. Bochkov (Author), R. V. Shevchenko (Author), V. V. Smirnov (Author), O. G. Grybakina (Author), A. A. Novitskyi (Author), V. P. Zherdev (Author), L. G. Kolik (Author), T. A. Gudasheva (Author), N. Yu. Ivashkina (Author)
• Formato: Livro
• Publicado em: LLC "Publisher OKI", 2017-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Results of pharmacokinetic study of a new dipeptide anxiolytic GB-115 in rats, rabbits and volunteers were presented. After oral drug administration significant differences were found. For example, a dose-independent parameter - the elimination rate constant was decreased: rat < human < rabbit...