Physiologically Based Pharmacokinetic (PBPK) Model of Gold Nanoparticle-Based Drug Delivery System for Stavudine Biodistribution

• Autori principali: Hinojal Zazo (Autore), Clara I. Colino (Autore), Carmen Gutiérrez-Millán (Autore), Andres A. Cordero (Autore), Matthias Bartneck (Autore), José M. Lanao (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Computational modelling has gained attention for evaluating nanoparticle-based drug delivery systems. Physiologically based pharmacokinetic (PBPK) modelling provides a mechanistic approach for evaluating drug biodistribution. The aim of this work is to develop a specific PBPK model to simulate stavu...