Mixed Lineage Leukemia 1 Promoted Neuron Apoptosis in Ischemic Penumbra via Regulating ASK-1/TNF-α Complex

• Autori principali: Zhang Feng (Autore), Liu Jie (Autore), Lv Guimin (Autore), Wang Xi (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Neuron apoptosis in ischemic penumbra was proved to be involved in ischemic stroke (IS) development and contributed to the poor prognosis of IS. Recent studies showed that aberrant trimethylation of histone H3 lysine 4 (H3K4me3) level was associated with cell apoptosis. This study aimed to explore t...