Inhibitory Effect of Azelastine on Allergic Itch-Associated Response in Mice Sensitized With Mosquito Salivary Glands Extract

• Main Authors: Eiji Ohtsuka (Author), Sanae Kawai (Author), Hiroshi Nojima (Author), Tsugunobu Andoh (Author), Kiyoshi Kamimura (Author), Yasushi Kuraishi (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined whether azelastine would inhibit itch-associated responses of mice to mosquito allergy. Repeated injections of mosquito salivary gland extract increased scratching and sensory nerve activity. Azelastine inhibited the increased scratching and nerve activity, while terfenadine was without...