Absence of effect of steady state bempedoic acid on cardiac repolarization: Results of a thorough QT/QTc study in healthy volunteers

Abstract Bempedoic acid is an inhibitor of adenosine triphosphate-citrate lyase approved for use in adults with hypercholesterolemia. Nonclinical studies assessed binding to the human ether‐a‐go‐go-related gene (hERG) potassium channel in vitro and the effect of bempedoic acid on QT/QTc in cynomolgu...

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Bibliografski detalji
Glavni autori: Benny M. Amore (Autor), Clay T. Cramer (Autor), Diane E. MacDougall (Autor), William J. Sasiela (Autor), Maurice G. Emery (Autor)
Format: Knjiga
Izdano: Wiley, 2021-11-01T00:00:00Z.
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