Deferasirox Causes Leukaemia Cell Death through Nrf2-Induced Ferroptosis

• Main Authors: Wan-Yi Hsu (Author), Li-Ting Wang (Author), Pei-Chin Lin (Author), Yu-Mei Liao (Author), Shih-Hsien Hsu (Author), Shyh-Shin Chiou (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lymphoblastic leukaemia (ALL) is the most prevalent cancer in children, and excessive iron buildup resulting from blood transfusions and chemotherapy potentially has a negative impact on treatment outcomes and prognosis in patients with ALL. Therefore, initiating early iron chelation therapy d...