Drug interactions between ALK inhibitors and warfarin with concurrent use of bucolome: a case report

• मुख्य लेखकों: Takashi Kato (लेखक), Yusuke Kunimoto (लेखक), Manabu Kitagawa (लेखक), Yuichiro Asai (लेखक), Tomoko Kimyo (लेखक), Hiromasa Nakata (लेखक), Mamoru Takahashi (लेखक), Hirofumi Chiba (लेखक), Hiroki Takahashi (लेखक), Atsushi Miyamoto (लेखक), Masahide Fukudo (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Alectinib, crizotinib, and ceritinib, are anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) that exhibit high protein binding, and their metabolism is associated with the cytochrome P450 (CYP) isoenzymes 2C9 or 3A4. The plasma protein binding rate of warfarin, whic...