In vitro Treatment with cis-[Ru(H-dcbpy-)2(Cl)(NO)] Improves the Endothelial Function in Aortic Rings with Endothelial Dysfunction

• Main Authors: Jorge Camargo Oishi (Author), Tereza Cristina Buzinnari (Author), Cezar Rangel Pestana (Author), Thiago Francisco De Moraes (Author), Izabela Pereira Vatanabe (Author), David Anderson Wink (Author), Roberto Santana Da Silva (Author), Lusiane Maria Bendhack (Author), Gerson Jhonatan Rodrigues (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The ruthenium complex cis-[Ru(H-dcbpy-)2(Cl)(NO)] (DCBPY) is a nitric oxide (NO) donor and  studies suggested that the ruthenium compounds can inactivate O2-. The aim of this study is to test if DCBPY can revert and/or prevent the endothelial dysfunction. Methods: Normotensive (2K) and hype...