Observational study of clinical outcomes for testosterone treatment of pubertal delay in Duchenne muscular dystrophy

• Main Authors: C. L. Wood (Author), T. D Cheetham (Author), K. G Hollingsworth (Author), M. Guglieri (Author), Y. Ailins-Sahun (Author), S. Punniyakodi (Author), A. Mayhew (Author), V. Straub (Author)
• Format: Book
• Published: BMC, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Adolescents with DMD treated with chronic high dose GC therapy typically have profound pubertal delay. Testosterone, the main circulating androgen in men, promotes virilisation and growth with associated accrual of fat-free muscle mass and bone mineral content. Testosterone thera...