Identification of two novel pathogenic variants of the NR1H4 gene in intrahepatic cholestasis of pregnancy patients

• Main Authors: Hua Lai (Author), Xianxian Liu (Author), Siming Xin (Author), Jiusheng Zheng (Author), Huai Liu (Author), Yu Ouyang (Author), Huoxiu Yang (Author), Yang Zeng (Author), Yang Zou (Author), Xiaoming Zeng (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Intrahepatic cholestasis of pregnancy (ICP) can cause adverse pregnancy outcomes, such as spontaneous preterm delivery and stillbirth. It is a complex disease influenced by multiple factors, including genetics and the environment. Previous studies have reported that functioning n...