Perpetuation of inflammation associated with experimental arthritis: the role of macrophage activation by neutrophilic myeloperoxidase

• Main Authors: Monique P. Gelderman (Author), Rodney Stuart (Author), David Vigerust (Author), Steven Fuhrmann (Author), Doris L. Lefkowitz (Author), Robert C. Allen (Author), Stanley S. Lefkowitz (Author), Susan Graham (Author)
• Format: Book
• Published: Hindawi Limited, 1998-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rheumatoid arthritis (RA) is characterized by an abnormal cellular and cytokine infiltration of inflamed joints. This study addresses a previously unrecognized interaction between neutrophilic-myeloperoxidase (MPO) and macrophages (MΦ) which could explain the perpetuation of inflammation associated...