Charcoal Hemoperfusion for Methotrexate Toxicity: A Safe and Effective Life-Rescue Alternative When Glucarpidase Is Not Available

• Egile Nagusiak: Alejandra Rosales (Egilea), Alvaro Madrid (Egilea), Marina Muñoz (Egilea), Jose Luis Dapena (Egilea), Gema Ariceta (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background: High dose methotrexate (HDMTX) is used for the treatment of pediatric hemato-oncological diseases. HDMTX can induce acute kidney injury in cases of delayed elimination. The use of leucovorin remains the most effective rescue action. Further treatment options are of difficult access in th...