Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions

Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions

A novel plant sesquiterpene lactone derivative, DET derivative (DETD)-35, originating from parental deoxyelephantopin (DET) was previously observed to effectively suppress human triple negative breast cancer (TNBC) MDA-MB-231 cell activity and tumor growth in mice. In this study, the mechanisms unde...

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Bibliographic Details
Main Authors: Jeng-Yuan Shiau (Author), Yong-Qun Chang (Author), Kyoko Nakagawa-Goto (Author), Kuo-Hsiung Lee (Author), Lie-Fen Shyur (Author)
Format: Book
Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
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