Unveiling the impact of CDK8 on tumor progression: mechanisms and therapeutic strategies

• Váldodahkkit: Xiaomin Yin (Dahkki), Zhilong He (Dahkki), Kun Chen (Dahkki), Kai Ouyang (Dahkki), Changxuan Yang (Dahkki), Jianjun Li (Dahkki), Hailin Tang (Dahkki), Manbo Cai (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

CDK8 is an important member of the cyclin-dependent kinase family associated with transcription and acts as a key "molecular switch" in the Mediator complex. CDK8 regulates gene expression by phosphorylating transcription factors and can control the transcription process through Mediator c...