Prediction of overall survival in patients across solid tumors following atezolizumab treatments: A tumor growth inhibition-overall survival modeling framework

• Main Authors: Phyllis Chan (Author), Mathilde Marchand (Author), Kenta Yoshida (Author), Shweta Vadhavkar (Author), Nina Wang (Author), Alyse Lin (Author), Benjamin Wu (Author), Marcus Ballinger (Author), Nitzan Sternheim (Author), Jin Y. Jin (Author), René Bruno (Author)
• Format: Book
• Published: Wiley, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The objectives of the study were to use tumor size data from 10 phase II/III atezolizumab studies across five solid tumor types to estimate tumor growth inhibition (TGI) metrics and assess the impact of TGI metrics and baseline prognostic factors on overall survival (OS) for each tumor type...