International consortium for innovation and quality: An industry perspective on the nonclinical and early clinical development of intravitreal drugs

• Main Authors: Ingrid M. Pruimboom‐Brees (Author), Swati Gupta (Author), Nagendra Chemuturi (Author), Helen S. Booler (Author), Erik Nimz (Author), Meg Ferrell Ramos (Author), Antonello Caruso (Author), Katie F. Maass (Author), Vladimir Bantseev (Author), Qihong Huang (Author), Mary P. Choules (Author), Jesse C. Nussbaum (Author), Jitendra Kanodia (Author), Christopher Thompson (Author), Chandrasekar Durairaj (Author)
• Format: Book
• Published: Wiley, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The eye, which is under constant exposure to environmental pathogens, has evolved various anatomic and immunological barriers critical to the protection of tissues lacking regenerative capacity, and the maintenance of a clear optic pathway essential to vision. By bypassing the ocular barrie...