Nicotine exacerbates diabetic nephropathy through upregulation of Grem1 expression

• Main Authors: Jianning Chen (Author), Haiting Xiao (Author), Rui Xue (Author), Vinod Kumar (Author), Rukhsana Aslam (Author), Syed Faizan Mehdi (Author), Huairong Luo (Author), Ashwani Malhotra (Author), Xiqian Lan (Author), Pravin Singhal (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Diabetic nephropathy (DN) is a major complication of diabetes mellitus. Clinical reports indicate that smoking is a significant risk factor for chronic kidney disease, and the tobacco epidemic exacerbates kidney damage in patients with DN. However, the underlying molecular mechan...