MiR-449a antagonizes EMT through IL-6-mediated trans-signaling in laryngeal squamous cancer

• Main Authors: Alessia Maria Cossu (Author), Federica Melisi (Author), Teresa Maria Rosaria Noviello (Author), Lucia Stefania Pasquale (Author), Piera Grisolia (Author), Carla Reale (Author), Marco Bocchetti (Author), Michela Falco (Author), Chiara Tammaro (Author), Nunzio Accardo (Author), Francesco Longo (Author), Salvatore Allosso (Author), Massimo Mesolella (Author), Raffaele Addeo (Author), Francesco Perri (Author), Alessandro Ottaiano (Author), Filippo Ricciardiello (Author), Evzen Amler (Author), Concetta Ambrosino (Author), Gabriella Misso (Author), Michele Ceccarelli (Author), Michele Caraglia (Author), Marianna Scrima (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNAs (miRNAs) are involved in post-transcriptional gene expression regulation and in mechanisms of cancer growth and metastases. In this light, miRNAs could be promising therapeutic targets and biomarkers in clinical practice. Therefore, we investigated if specific miRNAs and their target genes...