Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes

• Main Authors: Dominik Damm (Author), Ehsan Suleiman (Author), Hannah Theobald (Author), Jannik T. Wagner (Author), Mirjam Batzoni (Author), Bianca Ahlfeld (née Kohlhauser) (Author), Bernd Walkenfort (Author), Jens-Christian Albrecht (Author), Jidnyasa Ingale (Author), Lifei Yang (Author), Mike Hasenberg (Author), Richard T. Wyatt (Author), Karola Vorauer-Uhl (Author), Klaus Überla (Author), Vladimir Temchura (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Functionalization of experimental HIV-1 virus-like particle vaccines with heterologous T helper epitopes (T helper VLPs) can modulate the humoral immune response via intrastructural help (ISH). Current advances in the conjugation of native-like HIV-1 envelope trimers (Env) onto liposomes and encapsu...