Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti.

• Main Authors: Lucie Danet (Author), Guillaume Beauclair (Author), Michèle Berthet (Author), Gonzalo Moratorio (Author), Ségolène Gracias (Author), Frédéric Tangy (Author), Valérie Choumet (Author), Nolwenn Jouvenet (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>To be transmitted to vertebrate hosts via the saliva of their vectors, arthropod-borne viruses have to cross several barriers in the mosquito body, including the midgut infection and escape barriers. Yellow fever virus (YFV) belongs to the genus Flavivirus, which inclu...