Development and Characterization of Nanoliposomal Hydroxyurea Against BT-474 Breast Cancer Cells

• Main Authors: Azam Akbari (Author), Azim Akbarzadeh (Author), Morteza Rafiee Tehrani (Author), Reza Ahangari Cohan (Author), Mohsen Chiani (Author), Mohammad Reza Mehrabi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Hydroxyurea (HU) is a well-known chemotherapy drug with several side effects which limit its clinical application. This study was conducted to improve its therapeutic efficiency against breast cancer using liposomes as FDA-approved drug carriers. Methods: PEGylated nanoliposomes-containing...