Shikonin impairs mitochondrial activity to selectively target leukemia cells

• Main Authors: Alessia Roma (Author), Matthew Tcheng (Author), Nawaz Ahmed (Author), Sarah Walker (Author), Preethi Jayanth (Author), Mark D. Minden (Author), Julie A. Reisz (Author), Angelo D'Alessandro (Author), Jakub Rohlena (Author), Paul A. Spagnuolo (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy that results from the accumulation of undifferentiated myeloid cells in the peripheral blood and bone marrow. Limited therapeutics contribute to unfavorable patient outcomes, highlighting the need for novel therapeutics to improv...