Selective somatostatin receptor 5 inhibition improves hepatic insulin sensitivity

• Main Authors: Yumiko Okano Tamura (Author), Jun Sugama (Author), Shin‐ichi Abe (Author), Yuji Shimizu (Author), Hideki Hirose (Author), Masanori Watanabe (Author)
• Format: Book
• Published: Wiley, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Diabetes is a metabolic disorder with an increasing global prevalence. Somatostatin (SST), a peptide hormone, regulates hormone secretion via five SST receptor (SSTR) subtypes (SSTR1-5) in a tissue‐specific manner. As SSTR5 is expressed in pancreatic β‐cells and intestinal L‐cells, studies...